Neurexins and Autism
A few reasons why neurexin genes might be associated with autism.
- disrupt in function of synapses (& communication between neurons), which could contribute to the autistic social and communication challenges
- disruption in brain development as neurexin genes expressed early in brain development, and play important roles in the formation of neural circuits.
- impact on function of other genes as they interact with a number of other proteins.
Severe Weather Nashville - Winter Edition
March Snowfall, a Climate Change Call
Bits of fluff dance and sway
Cherry blossoms on a spring day
I watch from my window, in awe of this display.
Days should be bright and long
Unexpected snowfall, sign of larger exchange?
CRH who?
Stress v Anxiety in Autism - what's the difference.
Stress is when you're stuck in traffic and late for an important meeting, while anxiety is when you're stuck in traffic and your brain starts to imagine all the worst-case scenarios that could happen at the meeting. They both make you feel like you're about to lose your mind, but with anxiety, you have to deal with the added bonus of your own overactive imagination!
Before you speak, ask yourself
SSTPQ - The Self, Space, and Time Perception Questionnaire
Lexicon [Measures] - SSTPQ
The SSTPQ consists of 13 questions and measures three distinct constructs and aims to capture individuals' subjective experiences and perceptions related to cognition areas of.
- perception of time
- differentiation between self-voice and other-voice
- perception of PPS
Scoring is on a Likert scale and individual scores provide a total score. Interpretation may involve comparing the scores to established norms/controls
Limitations:
- Reliance on self report means social desirability bias and the limitations of introspection.
- Sub measures not explicitly stated
Potential Limitation in Autism Populations:
- Autistics may have atypical perceptions of time, self-voice and other-voice, and PPS.
- Sensory and cognitive processing differences in autism may influence the accuracy of self-report measures.
- Some may have difficulties expressing their experiences or perceiving these constructs in the same way as NT
- The SSTPQ may not capture the full range of submeasure variations observed in autism, as the questionnaire's dimensions and items may not align with the unique experiences and challenges faced by autistics
Remembering Judy @DREDF
Last year, I had been invited to join the DREDF board, my response to joining was a resounding YES.
At the first board meeting on Aug 12,2022, it was the late Judy Heumann who nominated me to the board and the motion was seconded by Christina Mills. The board voted unanimously to have me join the board.
Thinking of you Judy, as we head into the next board meeting without you today. You were there at start of DREDF to make it a reality and later on its board, and we will miss your presence.