Empathy is not just a trait, its a way of life.

Towards a more Humane Society. Contemplation, one line a day. This month Empathy


 

Neurexins and Autism

Neurexins had come up in my Cell Neuroscience course this semester. Connection to Autism. But of course!!


Neurexins are a family of proteins that play important roles in synaptic function. They are involved in the formation, maintenance, and plasticity of synapses, which are the junctions between neurons that allow them to communicate with each other. Mutations in neurexin genes have been linked to a number of neurodevelopmental disabilities, including autism.

A few reasons why neurexin genes might be associated with autism.
  • disrupt in function of synapses (& communication between neurons), which could contribute to the autistic social and communication challenges
  • disruption in brain development as neurexin genes expressed early in brain development, and play important roles in the formation of neural circuits.
  • impact on function of other genes as they interact with a number of other proteins.
More research is needed to understand the exact mechanisms by which mutations in neurexin genes mutations contribute to autism.

Empathy is the art of putting yourself in someone else's shoes

Towards a more Humane Society. Contemplation, one line a day. This month Empathy


 

Severe Weather Nashville - Winter Edition

Nashville sure has a lot of severe weather alerts. This is the running tab for Winter (Dec 21 - Mar 20). 

Empathy is the magic that turns strangers into friends

Contemplation, one line a day.Towards a more humane society, an empathic society. 

 

March Snowfall, a Climate Change Call

Snow flurries gently fall
Mercury dips to a 27F crawl.
Bits of fluff dance and sway
Cherry blossoms on a spring day
I watch from my window, in awe of this display.

Calendar March, the weather all wrong
Days should be bright and long
Unexpected snowfall, sign of larger exchange?
World upended by climate change

CRH who?

Neuroscience humor. Studying CRH-PVN neurons and stress this week. 

Knock knock.
Who's there? 
CRH. 
CRH who? 
CRH releasing PVN, causing stress to you!

Stress v Anxiety in Autism - what's the difference.



First a lighthearted take

Stress is when you're stuck in traffic and late for an important meeting, while anxiety is when you're stuck in traffic and your brain starts to imagine all the worst-case scenarios that could happen at the meeting. They both make you feel like you're about to lose your mind, but with anxiety, you have to deal with the added bonus of your own overactive imagination!

Before you speak, ask yourself

Before you speak, ask yourself: 
Is it kind?
Is it necessary?
Does it improve the silence?

-Sri Sathya Sai Baba

Empathy is the ability to understand without judgement

Contemplation, one line a day.Towards a more humane society, an empathic society. 

 

SSTPQ - The Self, Space, and Time Perception Questionnaire

Lexicon [Measures] - SSTPQ

 

The SSTPQ consists of 13 questions and measures three distinct constructs and aims to capture individuals' subjective experiences and perceptions related to cognition areas of.

  • perception of time
  • differentiation between self-voice and other-voice
  • perception of PPS

Scoring is on a Likert scale and individual scores provide a total score.  Interpretation may involve comparing the scores to established norms/controls

Limitations:

  • Reliance on self report means social desirability bias and the limitations of introspection.
  • Sub measures not explicitly stated

Potential Limitation in Autism Populations:

  • Autistics may have atypical perceptions of time, self-voice and other-voice, and PPS.
  • Sensory and cognitive processing differences in autism may influence the accuracy of self-report measures.
  • Some may have difficulties expressing their experiences or perceiving these constructs in the same way as NT
  • The SSTPQ may not capture the full range of submeasure variations observed in autism, as the questionnaire's dimensions and items may not align with the unique experiences and challenges faced by autistics

Frustration

Nothing seems to go my way
Stuck in this rut, I cannot escape

Remembering Judy @DREDF

Last year, I had been invited to join the DREDF board, my response to joining was a resounding YES. 

At the first board meeting on Aug 12,2022, it was the late Judy Heumann who nominated me to the board and the motion was seconded by Christina Mills. The board voted unanimously to have me join the board. 

Thinking of you Judy, as we head into the next board meeting without you today. You were there at start of DREDF to make it a reality and later on its board, and we will miss your presence.