In the search for Humanity (and our own mental health), let's take a pause for contemplation, one thought at a time. As we navigate the complexities of existence, let compassion be our guide, fostering empathy and connection. In the realm of self-discovery, let confidence be the cornerstone, a quiet strength that speaks volumes. Amidst the chaos, find solace in the simplicity of now. Unleash the boundless potential within, for creativity knows no boundaries. Cultivate a thirst for knowledge, for curiosity fuels the engine of growth.
Compassion
In the search for Humanity (and our own mental health), let's take a pause for contemplation, one thought at a time. As we navigate the complexities of existence, let compassion be our guide, fostering empathy and connection. In the realm of self-discovery, let confidence be the cornerstone, a quiet strength that speaks volumes. Amidst the chaos, find solace in the simplicity of now. Unleash the boundless potential within, for creativity knows no boundaries. Cultivate a thirst for knowledge, for curiosity fuels the engine of growth.
Altruism
Crimson Friday
Mixtape of Ambivalent Moods
In the morning light, I rise with a grin
(Refrain)
(Verse 2)
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(Verse 3)
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Suicide Mortality in Autistics
Trait Anxiety vs State Anxiety
Tse et al 2023 - Executive functioning, self-regulation, and physical exercise
Schwartzman 2023: suicidal behaviors in autistic adolescents
Key Takeaways
- Early adolescent autistics (total sample 239, 138 autistic) at higher risk for suicidal ideation and NSSI (non suicidal self-injurious behaviors) compared to non-autistics.
- 20% autistics reported suicide ideation on self-report questionnaires but not to a study psychiatrist (via the Columbia Suicide Severity Rating Scale)
- No sex based differences seen.
- What are the underlying factors that contribute to the higher risk of suicidal thoughts / behaviors and NSSI in autistic early adolescents?
- How can clinicians improve their ability to detect these behaviors given the discrepancies between self-report and clinician-rated measures?
- What interventions or treatments are effective in reducing the risk of these behaviors in autistic youth?
- How can parents, caregivers, and educators better support autistic youth who may be at risk ?
- What are the long-term outcomes for autistic youth with suicidal thoughts/behaviors and NSSI?
Schwartzman JM, Muscatello R, Corbett BA. Assessing Suicidal Thoughts and Behaviors and Nonsuicidal Self-Injury in Autistic and Non-Autistic Early Adolescents Using the Columbia Suicide Severity Rating Scale. Journal of Autism and Developmental Disorders 53.2 (2023): 559-570. doi:10.1177/136236132311621. PMID 30938385
April 13 is Autism Adolescence Day
Recognizing the transitions that come with adolescence in autism, along with the current inadequacy of needed supports, care and services. Translatable solutions are needed now.
- Social Isolation/Loneliness, Social Difficulties, fewer friendships/social contacts, lesser time spent on social activities (1,2,3)
- Mental health, suicide ideation and NSSI
- Bullying and victimization
- Navigating educational system & workplace due to social and communication difficulties
- Seizure onset 15% (compared to 0.5 - 1% in general population) (4).
- Higher prevalence of atypical or non-convulsive seizures in autistic teens compared to non-autistic (5).
- Increased prevalence of epilepsy in autistic teens (11.4%) compared to 0.5% in general population (6).
- Sleep disturbance at 50-80%- insomnia, nightmares, and irregular sleep-wake cycles (7).
- Sensory sensitivities at 88% (non-autistic teens 58%) (8).
- GI symptoms in autistic kids compared to non-autistic kids. In a 2014 study (9) figures are 43.5% compared to 18.1%. In a 2010 study (10), figures are 46-85% compared to 9-10%). Which means the prevalence is higher in autistic teens as well. 'Autistic teenagers at increased risk for anxiety, depression, and other mental health conditions.
- Co-occuring condition in 70% of autistics - anxiety disorders 41%, ADHD 31% & mood disorders 16% (11).
- Nuero-inflammatory markers in autistic teens
- Obesity 22.4% (general population 15.6%) (14)
- Asthma 22.2% (general population 12.8%) (15)
- Allergies 23.9% (general population 18.4%) (16)
MAST - The Maastricht Acute Stress Test
[concepts in Sensorimotor Research]
The Maastricht Acute Stress Test (MAST) is a research laboratory procedure that is used to induce stress in research participants. It is used to study the effects of stress on a variety of physiological and psychological processes, including heart rate, blood pressure, cortisol levels, anxiety, and depression. The MAST combines elements from two of the most common experimental paradigms measuring stress, the Trier Social Stress Test (TSST) and the Cold Pressor Test (CPT).
The Test:
There is a 5-minute preparation phase, during which the participant is seated in a comfortable chair and is given instructions about the task. The participant is then asked to put their right hand into a bowl of ice water for 60-90 seconds. In between each hand immersion trial, the participant is asked to complete a series of mental arithmetic problems. The participant is given negative feedback if they make a mistake or take too long to answer a question.
The test takes approximately 20 minutes to complete. During the procedure, the participant's heart rate, BP, and salivary cortisol levels are measured. The participant is also asked to rate their subjective feelings of stress on a scale of 1 to 10.
Benefits
- It is a simple and easy-to-use procedure.
- It is non-invasive and does not pose any risk to participants.
- It is effective at inducing stress in participants.
- It can be used to measure a variety of stress-related outcomes.
Limitations
- Laboratory-based procedures may not be representative of real-world stress.
- It can be stressful for participants and may not be suitable for everyone. (will autistics even agree to do this?)
- It is not a diagnostic tool and cannot be used to diagnose any medical conditions.
Crip Time needed anon
Anxiety in ASD
Went for a guest lecture by Dr. Trenesha Hill, Asst Prof at U Nebraska Medical Center.
Autism Solutions Month
We are way beyond talk of Awareness, way beyond talk of Acceptance, way beyond talk of Inclusion
We need TRANSLATABLE SOLUTIONS that actually assists us.
And we need it now.
I'm calling April, AUTISM SOLUTIONS MONTH
Propananol
Propanaol has come up in lectures in my Cell Neuroscience course this sem. Of personal interest to me, as its use has become prevalent in the autism population. My last set of docs at Stanford said they preferred its use as it has less side effects compared to other drugs. I have mixed feelings about it effectiveness in my case but I've heard its helping a number of other autistics.
The use of Propranolol (brand names - Inderal, Hemangeol, & InnoPran XL) in autism is actually off-label as some research has suggested that propranolol may be helpful with anxiety, social withdrawal and repetitive behaviors. More research is needed to fully understand its effectiveness in autism.
One concerning side effect is memory impairment. So I have to wonder about its long term impact as we age, as many autistics are on it for many years and years. Are we looking at short term gains and compromising our long term health compounding health issues that already accompany old age.
Hyperpolarized Neurons on Strike
Off on unplanned mental vacation.
Action potential needed anon.
Stress v Anxiety in Autism - what's the difference.
Stress is when you're stuck in traffic and late for an important meeting, while anxiety is when you're stuck in traffic and your brain starts to imagine all the worst-case scenarios that could happen at the meeting. They both make you feel like you're about to lose your mind, but with anxiety, you have to deal with the added bonus of your own overactive imagination!