CRH who?

Neuroscience humor. Studying CRH-PVN neurons and stress this week. 

Knock knock.
Who's there? 
CRH. 
CRH who? 
CRH releasing PVN, causing stress to you!


And a longer one
Knock Knock
Who's there?
CRH
CRH who?
CRH hormone activating HPA axis and releasing cortisol in response to stress. 
Oh I see, who's next?
PVN
PVN who?
PVN, the paraventricular nucleus of the hypothalamus that produced and releases CRH stress signals from the amygdala. 
Ah, got it. What's the punchline?
Stress is no match for CRH and PVN's ability to control it - they's the stress-busting duo. 


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Knock knock. 
Who's there? 
Stress. 
Stress who? 
Stress no more, it's the weekend!

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Knock knock. 
Who's there? 
Anxiety. 
Anxiety who? 
Anxiety friend, can you please distract me from my own thoughts?

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Stress: Hey Anxiety, why are you always so jittery? Don't you know how to relax?
Anxiety: I can't help it! You're the one who always makes me feel like the world is about to end.

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Knock, knock.
Who's there?
GABA, serotonin, norepinephrine, prefrontal cortex, amygdala, hippocampus, and more!
Stress and Anxiety: Ha ha, good one!
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Why did the stressed-out computer go to the doctor?
Because it had a virus and was feeling overwhelmed!

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