The Decerebrate Cat Walking Experiment
In the realm of scientific exploration, certain experiments push boundariesin ways not acceptable by modern ethical standards. One such experiment involves decerebrate cats (popular in the 1940-50s and not done anymore), but which shed light on locomotion,
The Decerebrate Cat Walking Experiment: The video showcases a decerebrate cat walking on a treadmill at varying speeds, revealing three distinct gait patterns. Decerebrate cats have had their cerebral cortex removed, leaving the brainstem intact. Essentially the cat was paralyzed as its spinal cord didn't talk to its brain anymore which means there was not enough muscle tone to keep the body upright; so researched used a harness to hold the weight of the body.
Locomotion was initiated by sensory input of the limbs on the moving thredmill.
The primary goal of these experiments was to explore the extent of the brain's involvement in controlling movement. At what level in the brain is behavior (locomotion) controlled. Researchers aimed to test the idea that much of locomotion control might be inherent to an animal's biomechanics, rather than relying heavily on conscious brain commands.
Findings:
- Minimal Brain Control: during locomotion, especially in activities like walking, trotting, or running, minimal control comes from the brain itself. Instead, the experiments suggest that a significant portion of locomotion control is achieved through biomechanical and morphological features of the animal's body.
- Biomechanical Design: The experiments support the concept of passive dynamic locomotion, which proposes that animals are capable of controlling their movements efficiently by taking advantage of their natural biomechanical structure.
Diagnostic Overshadowing Issue in Autism
Phrenology according to Gall. A Historical Curiosity
The prevailing view of the era was dominated by religious or philosophical beliefs rather than empirical research. Gall's ideas challenged long-held beliefs about the nature of the mind and the brain and landed in a lot of hot water.
And the hot water was not just religions, but also social. Phrenology also had practical implications, as some individuals and organizations began using it for character assessment in various contexts, such as education and employment. This raised ethical and legal questions about the fairness and validity of making judgments about people based on phrenological assessments.
Gall's most notable contribution was his intricate neuroanatomy diagram, which depicted the brain as a series of localized faculties or organs, each responsible for a particular aspect of personality or behavior. The size of these organs corresponded to a person's character traits and abilities. Obviously this is quite incredulous by today's standards - a historical curiousity.
- Firmness (in frontal lobe) Development of this area in the frontal lobe was associated with determination, willpower, and the ability to persevere in the face of challenges.
- Immortality: linked to religious and moral tendencies, as well as a sense of spirituality.
- Veneration (Parietal Love): related to feelings of respect, admiration, and reverence for authority figures or ideals
- Destructiveness (in lower back of brain): aggressive and combative behaviors, as well as a propensity for violence.
- Benevolence (frontal love): linked to kindness, empathy, and a compassionate nature.
- Acquisitiveness (forehead): desire for material wealth and possessions.
- Wit (Frontal Lobe): responsible for humor, quick thinking, and cleverness.
- Love of Offspring (back of brain):linked to parental instincts and the love and care of one's children.
- Secretiveness (Upper back of brain): associated with the tendency to keep secrets and be discreet.
- Self-Esteem (upper back of head): related to self-confidence, pride, and a sense of self-worth.
Code Orange for Ground Level Ozone
Received this email alert today on Air Quality. Thought I had left behind all the Air Quality Alerts in CA from the yearly wildfire smoke.
"Air Quality Alert.... Tennessee Department of Environment and Conservation has issued a Code Orange Health Advisory for the Nashville Area... Ground Level Ozone concentrations may approach unhealthy levels... active children and adults and people with respiratory issues ... should limit prolonged outdoor exertion."
So what exactly is Ground Level Ozone (also often referred to as "bad" ozone).
This is ozone that is not emitted directly into the air like some other pollutants. Instead, it forms in the atmosphere through a chemical reaction involving precursor pollutants in the presence of sunlight. Here is how it happens:
1. Emission of Precursor Pollutants: The primary precursor pollutants for ground-level ozone are nitrogen oxides (NOx) and volatile organic compounds (VOCs). These pollutants are released into the air from various sources, including vehicles (especially those with internal combustion engines), industrial processes, and natural sources like vegetation
2. Chemical Reactions: Once in the atmosphere, NOx and VOCs undergo a series of complex chemical reactions in the presence of sunlight. This process is known as photochemical smog formation. Sunlight provides the energy needed to break down these precursor pollutants and form ground-level ozone
3. Ozone Formation: The chemical reactions between NOx and VOCs produce ground-level ozone (O3) and other secondary pollutants. Ground-level ozone is a key component of smog and is harmful to human health when present in high concentrations near the Earth's surface.
Contemplation, one line a day
Contentment is the gratitude that comes with acknowledging what we have.
-Hari Srinivasan
Contemplation
Optimism is the force that keeps us moving forward, even when the path is unclear
- Hari Srinivasan
Saltafossi 2023 - The impact of cardiac phases on multisensory integration
The paper investigates how the cardiac phase affects multisensory integration, which is the process that allows information from multiple senses to combine non-linearly to reduce environmental uncertainty. The study found that the impact of the cardiac phase on multisensory integration may be specific for stimuli including somatosensory (i.e., tactile) inputs
Contemplation
Optimism is the fuel that propels us towards the horizon of possibilities.
- Hari Srinivasan
Dual Approach for Autism
My article in Newsweek
https://www.newsweek.com/dual-approach-autism-opinion-1818062
The nuances of research bias
Research is exclusionary in many ways, limited by bias and so many boundaries in the name of being able to clearly see particular results. So, in reality who does it actually serve?Loving Hari Srinivasan's article, and the nuanced things made clear when you read about his few experiences and insights caught in this one page.
Contemplation, one line a day
Contentment is the kindness that comes with accepting others as they are. - Hari Srinivasan
Stimming is not soothing
I wish folks stop saying stimming is soothing.
Stimming is soothing only upto a point. It quickly crosses over into OCD and is exhausting, mentally and physically draining, caught in this behavioral loop you cannot get out of.
Time Magazine Article
https://time.com/6299599/