Compassion is the light that shines in the eyes of those who care
Egocentric spatiotemporal perception
Disability in Strength
Compassion is the key that unlocks the door to forgiveness
Depersonalization and Autism
- Loss of body ownership /disembodiment feelings / somatosensory distortions/ loss of agency: distressing feelings of being 'spaced out', detached from one's self, body, and the world (observing yourself from a distance).
- atypical 'flat' time perception (alterations in perception, including disruptions in the perception of time. )
Research findings on DPD and atypical time perception in the NT population
- Distorted perception of time: Tendency to overestimate the duration of time intervals, perceiving time as slower than it actually is which can contribute to the overall sense of detachment (1,2)
- Neural correlates of time perception: fMRI studies show differences in brain activity and connectivity patterns in regions associated with time processing, eg: PFC and parietal cortex (3,4)
- Role of attentional processes: Difficulties in allocating attention appropriately, leading to a reduced ability to accurately perceive and process temporal information (5,6)
- Emotional factors: Emotional states, eg anxiety and stress, can modulate time perception, leading to temporal distortions. DP folks often experience heightened levels of anxiety and emotional distress, which may contribute to their altered perception of time. (1,2)
- Both involve atypical sensory processing suggesting a potential shared underlying connection.
- Overlap in Symptoms: Though there are distinct dx criteria, both share some overlapping symptoms, such as a sense of detachment from oneself, difficulties with emotional regulation, and social challenges.
- Neurobiological Factors: Though the specific mechanisms and neural circuits may differ, both potentially involve alterations in brain functioning and connectivity.
- Impact on Functioning: Co-occurrence may exacerbate the challenges in everyday functioning especially in areas of social interactions and emotional well-being.
- 17% autistics met the diagnostic criteria for DPD, compared to 2% non-autistic (7)
- Compared to controls, autism+DPD more likely to have
- higher anxiety and depression (8)
- more difficulty with social interaction and communication (9)
- more repetitive behaviors and special interests (10)
PD Soros Fall Conference
Compassion is the thread that weaves the fabric of society
What is Depersonalization Disorder
What is Depersonalization Disorder (DPD)?
Depersonalization Disorder (DPD) is a condition where people feel disconnected from their own body, self, and surroundings. This might feel like being "spaced out," watching yourself from a distance, or not feeling in control of your own actions. People with DPD may also have strange experiences with their senses and a warped sense of time, like feeling that time is moving slower than it really is.
Time Perception in DPD
- Distorted Time: People with DPD often feel that time moves slower, making them overestimate how long things take. This can add to their feeling of being detached.
- Brain Differences: Brain scans show that people with DPD have different brain activity in areas that process time, like the prefrontal cortex and parietal cortex.
- Attention Issues: People with DPD may have trouble focusing their attention, which makes it hard for them to accurately sense time.
- Emotional Impact: High anxiety and stress can change how people with DPD perceive time, making it feel even more distorted.
Why DPD May Happen Alongside Autism
- Sensory Processing: Both DPD and autism involve unusual ways of processing sensory information, suggesting a possible link.
- Similar Symptoms: While DPD and autism are different, they share some symptoms, like feeling detached from oneself and having trouble with emotions and social situations.
- Brain Function: Both conditions may involve changes in brain function and connectivity, although the specific details differ.
- Impact on Daily Life: Having both DPD and autism can make everyday tasks, social interactions, and emotional well-being more challenging.
Research Findings
- Prevalence: About 17% of autistic people have DPD, compared to 2% of non-autistic people.
- Additional Challenges: Autistic people with DPD are more likely to experience higher anxiety and depression, more difficulty with social interaction and communication, and more repetitive behaviors and special interests.
- Need for More Research: Understanding the connection between autism and DPD is complex, and more research is needed to uncover the full picture.
Self Referencing and Self Projecting
- Self-Referencing: general capacity of using one's own position in time to estimate/situate events in time. This skill relies on internal cues such as memory and self-awareness to place events within a temporal framework. By referencing our own experiences and the temporal context in which they occurred, we can make sense of the timing and sequence of events in our environment.
- Self-Projecting: ability to mentally move back and forward in time, maintaining the competence of correctly situating events in time. This skill allows us to anticipate future events, plan our actions, and make decisions based on the temporal context. Self-projecting skill involves mental time travel, where we can mentally simulate and project ourselves into different points in time, drawing upon past experiences and knowledge to predict and shape future events.
Suicide Mortality in Autistics
Autistic Inertia
Newton's first law of motion, the law of inertia, states that an object at rest remains at rest, and an object in motion continues in a straight line at constant velocity unless acted upon by an external force. This principle implies that an object maintains its state of motion or rest until a force induces a change.
Autistic Inertia
Autistic inertia can be conceptualized by drawing parallels to Newton's law of inertia, characterizing the difficulties some autistic individuals encounter in initiating and terminating tasks across behavioral, cognitive, and attentional domains.
Initiating Tasks (An Object at Rest Will Stay at Rest): Autistics frequently exhibit significant impairments in task initiation, akin to a state of behavioral or cognitive inertia. This may resemble catatonia [post on catatonia], necessitating substantial external stimuli to overcome the initial inertia and achieve task commencement.
Terminating Tasks (An Object in Motion Will Stay in Motion): Conversely, autistics often demonstrate difficulty in disengaging from tasks once initiated. This persistent engagement can lead to repetitive, unproductive behaviors or ruminative thoughts, paralleling obsessive-compulsive tendencies. Certain forms of stereotyped behaviors (e.g., stimming) may also reflect this aspect of inertia.
Neuroscientific manifestations of autistic inertia include:
- Task Transitioning: Deficits in neural mechanisms underlying task switching and cognitive flexibility, potentially involving the prefrontal cortex and parietal regions.
- Environmental Adaptation: Impaired adaptability to dynamically changing environments, possibly linked to disrupted sensory integration and motor planning circuits.
- Sustained Attention: Challenges in maintaining attention on tasks, which may involve dysregulation of the fronto-parietal attention network.
- Attention Mode Switching: Difficulty transitioning between focused and diffuse attention states, implicating the default mode network and attentional control systems.
- Executive Dysfunction: Impaired executive functions, including initiation, planning, and decision-making, associated with altered prefrontal cortex activity.
- Mental Health: Elevated anxiety and depression levels further complicate these cognitive and behavioral impairments.
These challenges contribute to a significant cognitive load, where initiating or stopping actions depletes cognitive resources ("spoons") [post on Spoon Theory], potentially leading to autistic burnout.
Etiology
Autistic inertia may arise from multiple neurobiological factors:
- Sensory Overload: Excessive sensory input leading to neural hyperactivity and cognitive overload.
- Motor Apraxia: Impairments in motor planning and execution, potentially involving the premotor cortex and supplementary motor area.
- Coordination Issues: Disruptions in motor coordination circuits, including the cerebellum and basal ganglia.
- Executive Dysfunction: Dysregulation of prefrontal-executive networks impacting task initiation and cognitive control.
- Anxiety: Heightened amygdala reactivity and dysregulated stress-response systems exacerbating cognitive and behavioral inertia.
These factors hinder the ability to complete tasks, adhere to schedules, and maintain employment or academic performance, often culminating in autistic burnout [post on autistic burnout].
Advantages
Paradoxically, the same neural mechanisms contributing to autistic inertia can facilitate hyper-focus, enabling intense concentration and expertise in specific areas.
Misconceptions
Autistic inertia is frequently misattributed to laziness or lack of motivation. Such misconceptions disregard the underlying neurocognitive and motor coordination challenges. Inertia is not exclusive to individuals with low support needs; it may be pronounced in those with concomitant movement disorders, sensory dysregulation, and motor coordination difficulties.
Interventions
Addressing autistic inertia necessitates targeted interventions:
- External Cues and Reminders: Utilizing external prompts to aid in task transitions.
- Personalized Support: Tailoring interventions to the individual's specific neurocognitive and sensory profiles.
Implementing these strategies can mitigate the impact of autistic inertia, enhancing daily functioning and reducing the risk of burnout.
Catatonia in Autism
Catatonia in autistic individuals is characterized by significant motor abnormalities, which can include immobility, rigid posturing, repetitive or stereotypic movements, and a markedly reduced responsiveness to external stimuli.
Catatonia in autism can present through various symptoms:
- Mutism: The inability to speak, which may be due to disruptions in neural circuits involving speech production and motor planning.
- Echolalia: The repetition of words or phrases, potentially linked to dysregulation in the neural pathways associated with language processing and executive function.
- Stereotypic Movements: Repetitive, non-functional movements that may involve neural dysfunctions in the basal ganglia and motor cortex.
- Posturing: The adoption and maintenance of unusual body positions, which could indicate abnormalities in motor planning and proprioceptive feedback systems.
- Stupor: A state of severe unresponsiveness, possibly associated with altered activity in the thalamocortical and limbic systems, affecting consciousness and responsiveness.
These manifestations suggest complex interactions between various neural systems, including the motor cortex, basal ganglia, cerebellum, and prefrontal cortex. Understanding the neural underpinnings of catatonia in autism can inform the development of targeted therapeutic interventions.
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Plain Language Version
Catatonia in Autism: What You Need to Know
Catatonia in autistic people means having big problems during a catatonia episode with movement and responding to the world around them. This can look like:
- Not Speaking (Mutism): Some autistic people with catatonia can't talk.
- Repeating Words (Echolalia): They might repeat words or phrases they hear.
- Repetitive Movements (Stereotypic Movements): They might move in the same way over and over.
- Holding Strange Positions (Posturing): They might stay in unusual body positions for a long time.
- Not Responding (Stupor): They might not respond to things happening around them.
These symptoms show that there are problems with how their brain controls movement and responds to the environment. Understanding these issues can help us find better ways to support and treat autistic people with catatonia.